Cannabidiol (CBD) has emerged as a very potent supplement over the years due to its anti-inflammatory properties that can help to combat several untreatable diseases that have ravaged the human race in the past years. Today, CBD oil is popularly used to treat cancer, improve schizophrenia symptoms, fight irritable bowel diseases, cure insomnia, and relieve anxiety among others.
CBD oil is one of the most beneficial substances that has been seen to offer a wide range of health solutions to majority of illnesses such as headaches, brain fog, infections, and a couple of chronic autoimmune disorders.
Cannabidiol (CBD) is a natural compound and one of the several cannabinoids that is found in Cannabis Sativa which is known as the marijuana plant. CBD and THC (Delta-9-tetrahydrocannabinol) are the most popular and two most active compounds found in cannabis plant. THC is psychoactive while CBD is non-psychoactive and does not have side effects such as paranoia, memory problems, and anxiety that is associated with using THC.
CBD oil and other compounds contained in cannabis have been found to possess potent cancer-fighting properties that has tremendously helped medical experts to record significant successes in the treatment of cancer. Although THC also has almost the same cancer-fighting ability but its use has been limited due to its psychoactive side effects when used in high doses. The ability of CBD to combat several types of cancer without any psychoactive side effects and the fact that it is also has a strong anti-tumor effects has seen its usage enjoy great acceptability in the health industry. CBD is also capable of preventing the growth of cancer cells in the body, it cures other ailment such as leukemia, lung disease, kills cervical cancer, decreases human brain cancer (glioma), colon cancer, thyroid, breast and prostate cancer among others.
CBD as an Anticancer
CBD acts as an anticancer mechanism by;
CBD serves as an antidote for certain pain-associated and inflammatory conditions. It acts on the body’s cannabinoid system to balance the immune system, protect from oxidative stress, and reduces inflammation.
CBD acts on the immune cells to trigger a host of antioxidant and anti-inflammatory reactions:
CBD reduces inflammatory immune products (Macrophage Inflammatory Protein-1) and it can also help to switch neutrophils to their anti-inflammatory state.
CBD is used to help relieve symptoms of multiple sclerosis in patients by reducing pains. Its combination with THC is also known to help with relieving pain, muscle tightness, combat sleep disorder, sleep disturbances and disorders.
CBD offers protection to the brain cells by countering the effects of oxidative and toxic substances in brain cells which makes it easier to recover from stroke and other forms of brain damage.
Studies have also shown that CBD can reduce uncontrolled muscle twitching, and a combination of CBD and THC was able to relieve muscle spasms in patients with multiple sclerosis in one study of 219 participants. However, when they were combined in a study of 17 patients with Parkinson’s disease, there was no improvement.
CBD is as well a stronger antioxidant than vitamin E (α-tocopherol) in cells or vitamin C (ascorbic acid). CBD can help those with Amyotrophic Lateral Sclerosis (ALS) live longer as a result of its antioxidant and anti-inflammatory properties.
To sum it all up, CBD can protect the brain from inflammation and damage, but it does not improve all movement problems associated with brain damage.
CBD helps to prevent psychosis and reduces symptoms of schizophrenia. Unlike THC, CBD does not trigger psychotic effects instead it produces antipsychotic effects and as a result of this it is gaining more ground as a natural alternative to antipsychotic drugs with less side effects.
CBD has the ability to reduce seizures in people with epilepsy. A 3-months study that was conducted in both children and adults showed that CBD can help to reduce seizures up to 39% with a maximum dosage of 25mg/kg/day.
CBD serves as a painkiller for people suffering from chronic pain. A combination of CBD and THC can help to reduce postoperative pain, cancer pain, neuropathic pain, rheumatoid arthritis, and chronic pains.
The antioxidant and anti-inflammatory properties of cannabinoids makes it a potent substance for relieving swelling and joint pains because it reduces disease worsening in inflammatory diseases like rheumatoid arthritis and it alleviates joint destruction.
Research has shown that Sativex (combination of CBD and THC) helps to reduce pains and arthritis symptoms as it was observed that the pain reduces with movement and at rest, it also reduces inflammation with improved sleep quality without any known side effects.
Several studies carried out the human brain have shown that a single dose of 400 mg reduces anxiety by limiting blood flow to certain parts of the limbic system that are the main actors in anxiety cases. Aside this, it increases blood flow to other important region responsible for motivation (the posterior cingulate cortex) and cognition. Its anxiety reduction effects extend to panic disorder, Post-Traumatic Stress Disorder (PTSD), and obsessive compulsive disorder among others.
CBD doses help to reduce vomiting and nausea that can be caused as a result of toxic drugs in animal studies.
For cancer patients, a well-balanced THC/CBD combination is the best option for reducing nausea and increasing appetite. The two tends to complement each other as the CBD reduces the psychotropic effects of THC but does not reduce appetite stimulation while THC does.
Marijuana which is a major constituents of CBD helps to lower BMI, less obesity and increase appetite. All these are known to have the effect of reducing the risk of having diabetes. Hence, since marijuana users have been known to lower insulin levels and fasting glucose by at least 16%, lower BMI and waist circumference, lower insulin resistance by 18%, and higher HDL, it naturally translates that marijuana reduces diabetes risk since all these factors are connected to the onset of diabetes.
Cannabidiol also helps to delay and prevent the destruction of insulin producing cells in the pancreas in a mouse study. It reduces inflammatory cytokines shifting the immune response from TH1 (autoimmune) to TH2 and as a result of this it is important for treating type 1 diseases because it has a strong autoimmune basis. Although, it can be used to prevent both Type 1 and type 2 diabetes.
Researcher have established the fact that CBD has an antidepressant effects in mice. Its depression-reducing effects in mice was fast, consistent over time, and as strong as any other antidepressant.
CBD helps to protect the heart by reducing inflammation, combating oxidative stress, and relaxing blood vessels among others. In animal models of heart diseases, it was observed that CBD protected the blood vessels from damage and relaxed the arteries by reducing irregular heart rhythms in various animal models. Hence, it is very vital preventing the brain from clogged blood vessel, protects from heart attack and stroke.
Studies and researches have shown that cellular and animal studies affirm that CBD is beneficial for inflammatory bowel disease (IBM). This is as a result of its proven anti-inflammatory effects. Studies have yet to confirm these benefits in human beings. CBD was able to prevent gut inflammation and normalized inflammation and gut motility in mice with IBD by acting on an important inflammation reducing and metabolic pathway (PPAR-gamma).
Research showed that CBD exhibits certain microbe-killing ability against methicillin staphylococcus Aureus (MRSA), a bacteria known to cause difficult-to-treat, and tricky infections.
The human bone has receptors for cannabinoids, though this is not common knowledge as only few people are aware of this. CBD enhanced the healing of broken limbs and also increased collagen structure in mice.
Studies have established the fact that cannabidiol contains prions, the proteins that cause fatal brain diseases (mad cow disease) as it was able to increase survival time of infected mice by up to a week.
Research have established the fact that inhaling CBD can help reduce or quit smoking. A pilot study of 24 smokers showed that cannabidiol reduced the number of cigarettes smoked by at least 40%, without increasing nicotine crave.
Dyskinesia is a kind of movement disorders which causes involuntary movements. It is a common side effect of schizophrenia therapy or Parkinson’s disease that causes severe involuntary movements of parts of the body. Study showed that CBD reduced the symptoms of dyskinesia in mice.
CBD decreased enzymes that enhance dyskinesia, and also reduced the production of inflammatory marker through the cannabinoid system and inflammatory pathways.
Research showed that when people with insomnia took CBD before going to sleep they experienced a better and deep sleep. It can be of good use for people with anxiety and Post-Traumatic Stress Disorder (PTSD) because it makes them sleep better due to its relaxing and anxiety-reducing effects.
CBD helps to reduce excessive division of the skin cells (keratinocytes), which could be beneficial for psoriasis.
CBD was able to reduce the use of opioid painkillers for people suffering from chronic pains. CBD serves as an alternative that is safe for people who may be affected from using too much of opioid to relief pain. It has the ability to interfere with the brain’s reward system in response to the opioids heroin and morphine.
CBD reduces the production of oils by the skin’s oil-producing glands by reducing the number of these glands as established by the study of tissue. Its anti-inflammatory effects are also an added benefit that make it potent for the treatment of acne. There are a lot of CBD-based skincare products in the market today.
The CBD Mechanisms
Primary Mechanisms through which CBD offers its many benefits include;
Side Effects and Safety
CBD is generally safe even when consumed at high doses. However, it still has some side effects and as such it consumption should be moderated. For example, CBD was discovered to decrease the activity of T and B cells, which may increase the growth of tumors, metastases, worsen HIV, asthma, and also increase the risk of infections. It is recommended that you should consult a medical expert to get the proper description of how it should be taken and in the right doses.
Other side effects that may be associated with CBD usage are as follows;
In conclusion, CBD oil possesses far more health benefits than the side effects that may come with using it and as a result of this, it has been legalized in several states in the United States.